Thursday, May 23, 2013

Risk Factor of Cervical Cancer

 
These factors may increase your risk of cervical cancer:
  • Many sexual partners. The greater your number of sexual partners — and the greater your partner's number of sexual partners — the greater your chance of acquiring HPV.
  • Early sexual activity. Having sex before age 18 increases your risk of HPV.
  • Other sexually transmitted infections (STIs). If you have other STIs — such as chlamydia, gonorrhea, syphilis or HIV/AIDS — the greater your chance is of also having HPV.
  • A weak immune system. Most women who are infected with HPV never develop cervical cancer. However, if you have an HPV infection and your immune system is weakened by another health condition, you may be more likely to develop cervical cancer.
  • Cigarette smoking. Smoking and HPV infection may work together to cause cervical cancer.

Vertigo


Benign paroxysmal positional vertigo (BPPV) is one of the most common causes of vertigo — the sudden sensation that you're spinning or that the inside of your head is spinning.
Benign paroxysmal positional vertigo is characterized by brief episodes of mild to intense dizziness. Symptoms of benign paroxysmal positional vertigo are triggered by specific changes in the position of your head, such as tipping your head up or down, and by lying down, turning over or sitting up in bed. You may also feel out of balance when standing or walking.
Although benign paroxysmal positional vertigo can be a bothersome problem, it's rarely serious except when it increases the chance of falls. You can receive effective treatment for benign paroxysmal positional vertigo during a doctor's office visit.

Causes Migraine


Although much about the cause of migraines isn't understood, genetics and environmental factors seem to both play a role.
Migraines may be caused by changes in the brainstem and its interactions with the trigeminal nerve, a major pain pathway. Imbalances in brain chemicals, including serotonin — which helps regulate pain in your nervous system — also may be involved.
Serotonin levels drop during migraine attacks. This may trigger your trigeminal system to release substances called neuropeptides, which travel to your brain's outer covering (meninges). The result is headache pain.
Migraine headache triggers
Whatever the exact mechanism of the headaches, a number of things may trigger them. Common migraine triggers include:
  • Hormonal changes in women. Fluctuations in estrogen seem to trigger headaches in many women with known migraines. Women with a history of migraines often report headaches immediately before or during their periods, when they have a major drop in estrogen. Others have an increased tendency to develop migraines during pregnancy or menopause. Hormonal medications — such as oral contraceptives and hormone replacement therapy — also may worsen migraines, though some women find it's beneficial to take them.
  • Foods. Some migraines appear to be triggered by certain foods. Common offenders include alcohol, especially beer and red wine; aged cheeses; chocolate; aspartame; overuse of caffeine; monosodium glutamate — a key ingredient in some Asian foods; salty foods; and processed foods. Skipping meals or fasting also can trigger migraine attacks.
  • Stress. Stress at work or home can instigate migraines.
  • Sensory stimuli. Bright lights and sun glare can induce migraines, as can loud sounds. Unusual smells — including pleasant scents, such as perfume, and unpleasant odors, such as paint thinner and secondhand smoke — can also trigger migraines.
  • Changes in wake-sleep pattern. Either missing sleep or getting too much sleep may serve as a trigger for migraines in some individuals, as can jet lag.
  • Physical factors. Intense physical exertion, including sexual activity, may provoke migraines.
  • Changes in the environment. A change of weather or barometric pressure can prompt a migraine.
  • Medications. Certain medications can aggravate migraines, especially oral contraceptives and vasodilators, such as nitroglycerin.

Causes Cancer


Cancer is ultimately the result of cells that uncontrollably grow and do not die. Normal cells in the body follow an orderly path of growth, division, and death. Programmed cell death is called apoptosis, and when this process breaks down, cancer begins to form. Unlike regular cells, cancer cells do not experience programmatic death and instead continue to grow and divide. This leads to a mass of abnormal cells that grows out of control.

Cancer

 
Cancer is a class of diseases characterized by out-of-control cell growth. There are over 100 different types of cancer, and each is classified by the type of cell that is initially affected.
Cancer harms the body when damaged cells divide uncontrollably to form lumps or masses of tissue called tumors (except in the case of leukemia where cancer prohibits normal blood function by abnormal cell division in the blood stream). Tumors can grow and interfere with the digestive, nervous, and circulatory systems, and they can release hormones that alter body function. Tumors that stay in one spot and demonstrate limited growth are generally considered to be benign.
Cancer cell
More dangerous, or malignant, tumors form when two things occur:
  1. a cancerous cell manages to move throughout the body using the blood or lymph systems, destroying healthy tissue in a process called invasion
  2. that cell manages to divide and grow, making new blood vessels to feed itself in a process called angiogenesis.
When a tumor successfully spreads to other parts of the body and grows, invading and destroying other healthy tissues, it is said to have metastasized. This process itself is called metastasis, and the result is a serious condition that is very difficult to treat.
How cancer spreads - scientists reported in Nature Communications (October 2012 issue) that they have discovered an important clue as to why cancer cells spread. It has something to do with their adhesion (stickiness) properties. Certain molecular interactions between cells and the scaffolding that holds them in place (extracellular matrix) cause them to become unstuck at the original tumor site, they become dislodged, move on and then reattach themselves at a new site.
The researchers say this discovery is important because cancer mortality is mainly due to metastatic tumors, those that grow from cells that have traveled from their original site to another part of the body. Only 10% of cancer deaths are caused by the primary tumors.
The scientists, from the Massachusetts Institute of Technology, say that finding a way to stop cancer cells from sticking to new sites could interfere with metastatic disease, and halt the growth of secondary tumors.
In 2007, cancer claimed the lives of about 7.6 million people in the world. Physicians and researchers who specialize in the study, diagnosis, treatment, and prevention of cancer are called oncologists.
Malignant cells are more agile than non-malignant ones - scientists from the Physical Sciences-Oncology Centers, USA, reported in the journal Scientific Reports (April 2013 issue) that malignant cells are much “nimbler” than non-malignant ones. Malignant cells can pass more easily through smaller gaps, as well as applying a much greater force on their environment compared to other cells.
Professor Robert Austin and team created a new catalogue of the physical and chemical features of cancerous cells with over 100 scientists from 20 different centers across the United States.
The authors believe their catalogue will help oncologists detect cancerous cells in patients early on, thus preventing the spread of the disease to other parts of the body
Prof. Austin said "By bringing together different types of experimental expertise to systematically compare metastatic and non-metastatic cells, we have advanced our knowledge of how metastasis occurs."

Heart Attack


Some heart attacks are sudden and intense — the "movie heart attack," where no one doubts what's happening. But most heart attacks start slowly, with mild pain or discomfort. Often people affected aren't sure what's wrong and wait too long before getting help. Here are signs that can mean a heart attack is happening:
  • Chest discomfort. Most heart attacks involve discomfort in the center of the chest that lasts more than a few minutes, or that goes away and comes back. It can feel like uncomfortable pressure, squeezing, fullness or pain.
  • Discomfort in other areas of the upper body. Symptoms can include pain or discomfort in one or both arms, the back, neck, jaw or stomach.
  • Shortness of breath with or without chest discomfort.
  • Other signs may include breaking out in a cold sweat, nausea or lightheadedness.
As with men, women's most common heart attack symptom is chest pain or discomfort. But women are somewhat more likely than men to experience some of the other common symptoms, particularly shortness of breath, nausea/vomiting, and back or jaw pain. Learn about the warning signs of heart attack in women.
heart attackLearn the signs, but remember this: Even if you're not sure it's a heart attack, have it checked out (tell a doctor about your symptoms). Minutes matter! Fast action can save lives — maybe your own. Don't wait more than five minutes to call 9-1-1 or your emergency response number. Watch this animation of a heart attack.
Calling 9-1-1 is almost always the fastest way to get lifesaving treatment. Emergency medical services (EMS) staff can begin treatment when they arrive — up to an hour sooner than if someone gets to the hospital by car. EMS staff are also trained to revive someone whose heart has stopped. Patients with chest pain who arrive by ambulance usually receive faster treatment at the hospital, too. It is best to call EMS for rapid transport to the emergency room.

Treatment Options for HIV/AIDS


Currently, there is no vaccine or cure for HIV/AIDS. But treatments have evolved which are much more efficacious - they can improve patients' general health and quality of life considerably.
Emergency HIV pills. If an individual believes they have been exposed to the virus within the last 72 hours (three days), anti-HIV medication, called PEP (post-exposure prophylaxis) may stop infection. The treatment should be taken as soon as possible after contact with the virus.

PEP is a very demanding treatment lasting four weeks. It is also associated with unpleasant side effects (diarrhea, malaise, nausea, weakness and fatigue).

After a positive HIV diagnosis, regular blood tests are necessary to monitor the progress of the virus before starting treatment. The therapy is designed to reduce the level of HIV in the blood.
Antiretroviral drugs. HIV is treated with antiretrovirals (ARVs). The treatment fights the HIV infection and slows down the spread of the virus in the body. Generally, patients take a combination of medications called HAART (highly active antiretroviral therapy).

The combination of drugs is adapted to each individual. HIV treatment is usually permanent and lifelong. HIV treatment is based on routine dosage. Pills must be taken on a regular schedule, every time. Common side effects include nausea, fatigue, diarrhea, skin rashes, moodiness, alterations to the adipose (fat) tissue, birth defects.
HIV/AIDS and diarrhea - HIV-positive patients, and those with AIDS tend to suffer from diarrhea. It is the main reason people go off their medications, or switch to other antiretroviral therapies prematurely. On January 2nd 2013, the US Food and Drug Administration approved Fulyzaq (crofelemer 125 mg delayed-release tablets), the first anti-diarrheal medication for patients with HIV/AIDS. Fulyzaq was created specifically for patients taking antiretroviral therapy for HIV/AIDS.
Complementary or alternative medicine. Although widely used, alternative/complementary medications, such has herbal ones, have not been proven to be effective or ineffective. According to some limited studies, mineral or vitamin supplements may provide some benefits. Patients are urged to discuss these options with their doctors.

Causes HIV/AIDS


HIV is a retrovirus that infects the vital organs of the human immune system. The disease progresses in the absence of antiretroviral therapy. The rate of disease progression varies widely between individuals and depends on many factors (age of the patient, body's ability to defend against HIV, access to health care, existence of coexisting infections, the infected person's genetic inheritance, resistance to certain strains of HIV).

HIV can be transmitted through:
  • Sexual transmission. It can happen when there is contact with infected sexual secretions (rectal, genital or oral mucous membranes). This can happen while having unprotected sex, including vaginal, oral and anal sex or sharing sex toys with someone infected with HIV.

  • Perinatal transmission. The mother can pass the infection on to her child during childbirth, pregnancy, and also through breastfeeding.

  • Blood transmission. The risk of transmitting HIV through blood transfusion is nowadays extremely low in developed countries, thanks to meticulous screening and precautions. Among drug users, sharing and reusing syringes contaminated with HIV-infected blood is extremely hazardous.

    Thanks to strict protection procedures the risk of accidental infection for healthcare workers is low.

    Individuals who give and receive tattoos and piercings are also at risk and should be very careful.

Difference Between HIV and AIDS


HIV is the virus which attacks the T-cells in the immune system. AIDS is the syndrome which appears in advanced stages of HIV infection. HIV is a virus. AIDS is a medical condition.

HIV infection causes AIDS to develop. However, it is possible to be infected with HIV without developing AIDS. Without treatment, the HIV infection is allowed to progress and eventually it will develop into AIDS in the vast majority of cases.

HIV testing can identify infection in the early stages. This allows the patient to use prophylactic (preventive) drugs which will slow the rate at which the virus replicates, delaying the onset of AIDS.

AIDS patients still have the HIV virus and are still infectious. Someone with AIDS can pass HIV to someone else.

Dangers of high cholesterol levels


High cholesterol levels can cause:
  • Atherosclerosis - narrowing of the arteries.

  • Higher coronary heart disease risk - an abnormality of the arteries that supply blood and oxygen to the heart.

  • Heart attack - occurs when the supply of blood and oxygen to an area of heart muscle is blocked, usually by a clot in a coronary artery. This causes your heart muscle to die.

  • Angina - chest pain or discomfort that occurs when your heart muscle does not get enough blood.

  • Other cardiovascular conditions - diseases of the heart and blood vessels.

  • Stroke and mini-stroke - occurs when a blood clot blocks an artery or vein, interrupting the flow to an area of the brain. Can also occur when a blood vessel breaks. Brain cells begin to die.

Wednesday, May 22, 2013

Symptoms of Typhus


Symptoms of murine or endemic typhus may include:
  • Abdominal pain
  • Backache
  • Dull red rash that begins on the middle of the body and spreads
  • Extremely high fever (105 - 106 degrees Fahrenheit), which may last up to 2 weeks
  • Hacking, dry cough
  • Headache
  • Joint and muscle pain
  • Nausea
  • Vomiting
Symptoms of epidemic typhus may include:
  • Chills
  • Confusion
  • Cough
  • Delirium
  • High fever (104 degrees Fahrenheit)
  • Joint pain (arthralgia)
  • Lights that appear very bright; light may hurt the eyes
  • Low blood pressure
  • Rash that begins on the chest and spreads to the rest of the body (except the palms of the hands and soles of the feet)
  • Severe headache
  • Severe muscle pain (myalgia)
  • Stupor
The early rash is a light rose color and fades when you press on it. Later, the rash becomes dull and red and does not fade. People with severe typhus may also develop small areas of bleeding into the skin (petechiae).

Typhus


       Typhus is caused by one of two types of bacteria: Rickettsia typhi or Rickettsia prowazekii.
Rickettsia typhi causes murine or endemic typhus.
  • Endemic typhus is uncommon in the United States. It is usually seen in areas where hygiene is poor and the temperature is cold. Endemic typhus is sometimes called "jail fever." The bacteria that causes this type is usually spread by rats to fleas to humans.
  • Murine typhus occurs in the southern United States, particularly California and Texas. It is often seen during the summer and fall. It is rarely deadly. You are more likely to get this type of typhus if you are around rats feces or fleas, and other animals  such as cats, opossums, raccoons, and skunks.
Rickettsia prowazekii causes epidemic typhus. It is spread by lice. Brill-Zinsser disease is a mild form of epidemic typhus.  It occurs when the bacteria re-activates in a person who was previously infected. It is more common in the elderly. 


Excercise for Osteoporosis and Osteoarthritis



       Osteoporosis and arthritis do share many coping strategies. With either or both conditions, people benefit from arthritis-friendly excercise programs that may include physical therapy and rehabilitation. In general, exercises that emphasize stretching, strengthening, posture, and range of motion are appropriate, such as:

  • low impact aerobics
  • walking
  • swimming and water excercise
  • Tai chi
  • low stress yoga

People with osteoporosis must take care to avoid activities that include bending forward from the waist, twisting the spine, or lifting heavy weights. People with arthritis must compensate for limited movement in arthritic joints. Always check with your physician to determine if a certain exercise or exercise program is safe for your specific medical situation.

Osteoarthritis



       Osteoarthritis a painful, degenerative joint disease that often involves the hips, knees, neck, lower back, or the small joints of the hands. Osteoarthritis usually develops in joints that are injured by repeated overuse in the performance of a particular job or a favorite sport or from carrying around excess body weight. Eventually this injury or repeated impact thins or wears away the cartilage that cushions the ends of the bones in the joint so that the bones rub together, causing a grating sensation. Joint flexibility is reduced, bony spurs develop, and the joint swells. Usually, the first symptom a person has with osteoarthritis is pain that worsens following exercise or immobility.
       Rheumatoid arthritis is an autoimmune inflammatory disease. An autoimmune disease is one in which the body releases enzymes that attack its own healthy tissues. In rheumatoid arthritis, these enzymes destroy the linings of joints causing pain, swelling, stiffness, deformity, and reduced movement and function. People with rheumatoid arthritis also may have systemic symptoms.

Osteoporosis



       Osteoporosis is a major health threat for 44 million Americans, 68% of whom are women. In osteoporosis, there is a loss of bone tissue that leaves bones less dense and prone to fracture. It can result in a loss of height, severe back pain and deformity. Osteoporosis can impair a person’s ability to walk and can cause prolonged or permanent disability.
       Osteoporosis is a silent disease that can often be prevented. However, if undetected, it can progress for many years without symptoms until a fracture occurs. Osteoporosis is diagnosed by a bone mineral density (BMD) test, a safe and painless way to detect low bone density.
Risk factors for developing osteoporosis include:
  • thinness or small frame
  • family history of osteoporosis
  • being postmenopausal or having had early menopause
  • abnormal absence of menstrual periods
  • prolonged use of certain drugs, such as prednisone
  • low calcium intake
  • physical inactivity
  • smoking
  • excessive alcohol intake